Publications

Pre-Prints

  1. Courtney E. Yaeger, Raúl Mojica Soto-Albors, Weizhuo Liu, Anna Beltramini, Mark T. Harnett (2025) Plateau potentials are instructive signals for behavioral timescale synaptic plasticity in the neocortex. bioRxiv 2025.11.07.687250; doi: https://doi.org/10.1101/2025.11.07.687250

  2. Valerio Francioni, Anna Beltramini, Linlin Z Fan, Mark T. Harnett (2025) CLOOSE: An open-source platform for optical closed-loop experiments. bioRxiv 2025.04.09.648061; doi: https://doi.org/10.1101/2025.04.09.648061

Publications

  1. Valerio Francioni, Vincent D Tang, Norma J. Brown, Enrique H.S. Toloza, Mark Harnett (2026) Vectorized instructive signals in cortical dendrites | Nature. doi: 10.1038/s41586-026-10190-7

  2. Dimitra Vardalaki, Trang L. D. Pham, Matthew P. Frosch, Garth Rees Cosgrove, Mark Richardson, Sydney S. Cash, Mark T. Harnett (2025) Patch2MAP combines patch-clamp electrophysiology with super-resolution structural and protein imaging in identified single neurons without genetic modification | Scientific Reports. doi: 10.1038/s41598-025-18207-3

  3. Voigts J, Kanitscheider I, Miller NJ, Toloza EHS, Newman JP, Fiete IR, Harnett MT. (2025) Spatial reasoning via recurrent neural dynamics in mouse retrosplenial cortex. Nat Neurosci. PMID: 40481228

  4. Newman J., Zhang J., Cuevas-López A., Miller N., Honda T., van der Goes M., Leighton A., Carvalho F., Lopes G., Lakunina A., Siegle J., Harnett MT., Wilson M., Voigts J. (2025) A unified open-source platform for multimodal neural recording and perturbation during naturalistic behavior. Nat Methods. PMCID: PMC11725498

  5. Vardalaki D., Yaeger C., Harnett MT. (2025) Silent Synapses in the Adult Brain. Annu Rev Neurosci. PMID: 39999855.

  6. Yaeger C., Vardalaki D., Zhang Q., Pham T., Brown N., Ji N., Harnett MT. (2024) A dendritic mechanism for balancing synaptic flexibility and stability. Cell Reports. PMID: 39167486

  7. van der Goes, M., Voigts, J., Newman, J., Toloza, E., Brown, N., Murugan, P., Harnett, M. (2024) Coordinated head direction representations in mouse anterodorsal thalamic nucleus and retrosplenial cortex.eLife. PMCID: 38470232

  8. Ding, W., Fischer, L., Chen, Q., Li, Z., Yang, L., You, Z., Hu,K., Wu,X., Zhou, X.,Chao, W., Hu, P., Dagnew, T.M., Dubreuil, D., Wang,S., Xia, S., Bao, C., Zhu, S., Chen,L., Wang, C., Wainger, B., Jin, P., Mao, J., Feng, G., Harnett, M.T., Shen. S. (2023). Highly synchronized cortical circuit dynamics mediate spontaneous pain. Journal of Clinical Investigation. PMCID: PMC10664135

  9. Vardalaki, D., Chung, K. & Harnett, M.T., (2022) Filopodia are a structural substrate for silent synapses in adult neocortex. Nature. PMID: 36450984

  10. Lafourcade et al., (2022) Differential dendritic integration of long-range inputs in association cortex via subcellular changes in synaptic AMPA-to-NMDA receptor ratio, Neuron. PMID: 35180389

  11. Beaulieu-Laroche, L., Brown, N.J., Hansen, M. et al (2021) Allometric rules for mammalian cortical layer 5 neuron biophysics. Nature. PMID 34759318

  12. Francioni V, Harnett MT (2021) Rethinking Single Neuron Electrical Compartmentalization: Dendritic Contributions to Network Computation In Vivo. Neuroscience. PMID 34116137

  13. Kim T, Chaloner FA, Cooke SF, Harnett MT, Bear MF (2020) Opposing Somatic and Dendritic Expression of Stimulus-Selective Response Plasticity in Mouse Primary Visual Cortex. Front Cell Neuroscience.PMID 32009901

  14. Fischer LF, Mojica Soto-Albors R, Buck F, Harnett MT (2020) Representation of visual landmarks in retrosplenial cortex. Elife. 9. PMID 32154781

  15. Newman JP, Voigts J, Borius M, Karlsson M, Harnett MT, Wilson MA (2020) Twister3: a simple and fast microwire twister. Journal of Neural Engineering. PMID 32074512

  16. Voigts J, Newman JP, Wilson MA, Harnett MT (2020) An easy-to-assemble, robust, and lightweight drive implant for chronic tetrode recordings in freely moving animals. Journal of Neural Engineering. PMID 32074511

  17. Voigts J, Harnett MT (2020) Somatic and dendritic encoding of spatial variables in retrosplenial cortex differs during 2D navigation. Neuron 105(2):237-245

  18. Beaulieu-Laroche L, Toloza EHS, Brown NJ, Harnett MT (2019). Widespread and highly correlated somato-dendritic activity in cortical layer 5 neurons. Neuron103(2):235-241

  19. Ranganathan GN, Apostolides PF, Harnett MT, Xu NL, Druckmann S, Magee JC (2018). Active dendritic integration and mixed neocortical network representations during an adaptive sensing behavior. Nature Neuroscience 21(11):1583-90

  20. Beaulieu-Laroche L, Toloza EHS, van der Goes MS, Lafourcade M, Barnagian D, Williams ZM, Eskandar EN, Frosch MP, Cash SS, Harnett MT (2018). Enhanced dendritic compartmentalization in human cortical neurons. Cell 175(3):643-651

  21. Beaulieu-Laroche L & Harnett MT (2018). Dendritic spines prevent synaptic voltage clamp. Neuron97(1):75-82

  22. Shin Yim Y, Park A, Berrios J, Lafourcade M, Pascual LM, Soares N, Yeon Kim J, Kim S, Kim H, Waisman A, Littman DR, Wickersham IR, Harnett MT, Huh JR, Choi GB (2017). Reversing behavioural abnormalities in mice exposed to maternal inflammation.Nature 549(7673):482-487